There are several ways to simplify that process.
With the Business edition you have a copy button in order to be able to copy your products. So if all your products use the same variants with the same prices, you can just set them for one and copy your product and then just change the description/name/image... That can be the case if you're selling photos in different size for example.
Also, you have the possibility use custom item fields (via the menu Display->Custom fields in the Business edition) for the characteristics which don't change the price. So for example, if you have the characteristics size and color for all your products, but that the color doesn't change the price, you can just add a custom item fields for the color and have only one characteristic for the size.
Finally, you can also use the CSV import to easily enter the different prices. Just get the product code of your variants and import from the textarea with something like this:
product_code,price_value
variant_1,10
variant_2,10
variant_3,10
variant_4,20
variant_5,20
variant_6,20
That should enable you to enter long list of prices quite rapidly with some copy/paste