Hi,
Probably because that's the only page on your backend were you have so many options.
For example, if you have a limit of 128 parameters per POST request, probably only that page of your backend has more tha this amount of parameters.
If you want to test if it comes from that, delete some of the tabs of the configuration page in the developer tools of your browser and then save the configuration and it should then work fine which points to the fact that there is a limit on the number of parameters on your server
But it could also be something else. For example, a security extension which depends a potential strange parameter on the HikaShop configuration form (and while it's not a threat, the security extension might not be tweaked correctly enough to understand that). And that wya you would also only get that error on the configuration form.